The work in my lab revolves around the molecular mechanisms of disease resistance in potato. Plant diseases are among the greatest deterrents to crop production worldwide. Diseases caused by fungi, viruses, bacteria, insects, and nematodes impact agronomic and horticultural crops, in addition to commercial and recreational forests. Major efforts have been devoted to understanding the mechanisms of genetic resistance and incorporating it into breeding programs to offset potential yield loss caused by pathogens. We hope that by understanding the molecular and genetic basis of resistance in plants, we can improve the process of developing new crop varieties that require less pesticide application.